science
One drug, two cleanup crews: A built-in backup for targeted protein degradation
Phys.org
May 12, 2026 · 20s listen
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One drug, two cleanup crews: A built-in backup for targeted protein degradation
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Most drugs work by inhibition: they block a protein's activity but leave the protein itself intact. Targeted protein degradation takes a fundamentally different approach, harnessing the cell's own quality-control machinery to remove proteins entirely.
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